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Page 2
All (n = 49)
Good outcome (mRS ≤ 3)
(n = 18)
Poor outcome (mRS > 3) (n = 31)
P value
Male
27 (55)
9 (50)
18 (58)
0.28
Age (years)
55 [44–70]
52 [39–64]
56 [45–71]
0.11
Chronic alcohol abuse
17 (35)
5 (28)
12 (39)
0.23
Diabetes
29 (59)
8 (44)
21 (68)
0.01
SAPS II
55 [49–60]
54 [44–61]
55 [50–60]
0.75
mRS prior to ICU admission
1 [0–2]
0 [0–1]
1 [0–2]
0.03
Etiology
Insulin and/or oral antidiabetics
32 (65)
12 (67)
20 (65)
0.89
Neuroendocrine carcinoma
8 (16)
2 (11)
6 (19)
Alcohol abuse
2 (4)
1 (6)
1 (3)
Adrenal insufficiency
1(2)
1 (6)
0 (0)
Unknown
6 (12)
2 (11)
4 (13)
Duration of hypoglycemia, min (n = 27)
480 [35–720]
45 [30–120]
660 [187–1283]
0.006
Initial glycemia (g/L)
0.21 ± 0.02
0.22 ± 0.03
0.20 ± 0.02
0.51
Glycemia on ICU admission (g/L)
1.01 ± 0.58
1.05 ± 0.16
1.50 ± 0.44
0.45
GCS
Initial
4 ± 1
4 ± 1
4 ± 1
0.45
After glycemia normalization
5 ± 1
5 ± 2
5 ± 1
0.89
Seizures
8 (16)
6 (33)
2 (6)
<0.001
Temperature (°C)
Initial
36.6 ± 0.2
36.7 ± 1.2
36.7 ± 0.5
0.91
Highest during first 24 h
37.9 ± 0.8
37.7 ± 0.8
38.0 ± 1.2
0.36
Initial arterial pH
7.38 ± 0.08
7.36 ± 0.12
7.40 ± 0.06
0.23
Initial lactate level (mmol/L)
2.54 ± 0.67
3.23 ± 1.36
2.10 ± 1.75
0.17
Time to final glycemia normalization (min)
180 [60–705]
480 [120–720]
180 [67–630]
0.78
Mechanical ventilation
46 (94)
16 (89)
30 (97)
0.55
Length of mechanical ventilation (days)
7 [3–12]
4.5 [2–8]
8 [6–13]
0.08
Normal EEG (n = 34)
1(3)
1 (10)
0 (0)
0.37
Normal brain imaging (n = 45)
25 (55)
11 (73)
14 (46)
0.009
Acquired ICU complications
Pneumonia
25 (51)
8 (44)
17 (55)
0.28
Septic shock
8 (16)
3 (17)
5 (16)
0.78
ICU length of stay (days)
11 [5.5–17]
8 [4–14]
11 [7–17]
0.57
At least 1-year follow-up, days (n = 27)
840 [394–1768]
826 [407–1906]
1373 [388–1997]
0.93
Values are n(%), mean ± SD or median [IQR]
GCS Glasgow Coma Score, SAPS II Simplified Acute Physiological Score (version II)
